|
KMID : 0928320060060030179
|
|
Korean Journal of Health Promotion and Disease Prevention
2006 Volume.6 No. 3 p.179 ~ p.185
|
|
|
Cardiovascular disease risk in male obstructive sleep apnea patients
|
|
Hwang Byung-Yun
Lee Geon-Ho
Suh Young-Sung
Kim Dae-Hyun
Ahn Byung-Hoon
Cho Yong-Won
Hwang Sang-Hee
|
|
|
Abstract
|
|
|
Background: Obstuctive sleep apnea(OSA) is a relatively common disorder that the prevalence is 1%-4% in adult men. It was previously assumed that this occurred because of the related obesity, however, recent data suggests that OSA may also be associated with a number of cardiovascular risk factors independently of obesity, such as hypertension, insulin resistance, impaired glucose tolerance and dyslipidemia. We studied to find the general characteristics and relation between OSA and cardiovascular disease by using Framingham risk score in Korean.
Methods: We enrolled 96 subjects in the three groups that group 1 was 28 who were snoring with AHI < 5. Group 2 was 35 subjects who were snoring with 5 ≤ AHI < 20, and group 3 was 33 who were snoring with AHI ≥ 20. We checked a
basic questionnaire, physical examination, blood test, polysomnography, and searched cardiovascular 10-year risk of three groups by Framingham risk score.
Results: Fasting blood glucose was a statistically significant difference between groups after adjustment for BMI, but lipid profiles and blood pressure were statistically not significant difference between groups. The summing score of systolic blood pressure(P=0.021) and total score(P=0.013) were a statistically significant difference in cardiovascular 10-year risk between groups. This study showed that 10-year cardiovascular risks by Framingham risk score estimated 2% in simple snoring subjects(group 1) and 6% in OSA subjects(group 2, 3).
Conclusions: In this study, OSA patients have high risk for cardiovascular disease in comparing cardiovascular 10 year risk by Framingham risk score. Therefore, primary care physician should concern about underdiagnosed OSA and know various practical approach to improve the symptoms. (Korean J Health Promot Dis Prev 2006 ; 6(3) : 179~185)
|
|
|
KEYWORD
|
|
|
obstructive sleep apnea, cardiovascular risk factor, Framingham risk score
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|